Adjunct Testosterone Implant Therapy in Breast Cancer Patients" We are developing a treatment for patients that we intend to improve quality of life, improve metabolic health, possibly lower the risk of recurrent cancer and can be continued for the rest of your life.
First a brief explanation of normal female hormone function. While most people believe that estrogen is the female and testosterone is the male hormone this is not actually true. Testosterone is the most abundant hormone in women. A healthy young woman will have ten times higher levels than estrogen. Estrogen is the reproductive hormone women only have high levels during pregnancy.
When Testosterone was first isolated in 1935 it was quickly discovered that in the laboratory T could kill breast cancer cells and Testosterone was used to treat breast cancer in the 1940's, 50's and into the 60's. With new treatments it was forgotten about until early 2000's.
A breast cancer surgeon working with a researcher at the National Institute of Health have done research for the past 20 years showing the benefits to T in both breast cancer patients and menopausal women without breast cancer. You can access all this research and hormonebalance.org/publications.
In summary the research shows that menopausal women with symptoms of hormone deficiency treated with Testosterone implants can control the symptoms of menopause and may lower their risk of developing breast cancer up to 39%.
In breast cancer patients who should be taking Tamoxifen or an Aromatase Inhibitor but cannot tolerate because of side effects the Testosterone implants may decrease the side effects so patients can be on the treatment they need.
In breast cancer survivors who are no longer on any treatment the T implants may improve quality of life, improve metabolic health while and hopefully decrease the risk of recurrent breast cancer. This is what our study intends to prove.